Agencies report over 3,000 AI use cases in 2025
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The number of reported use cases more than doubled from 2024, revealing the federal government’s continued appetite to acquire advanced artificial intelligence for its workflows.
The Office of Management and Budget unveiled the completed 2025 Federal Agency Artificial Intelligence Use Case Inventory, documenting 3,611 individual use cases across 56 submitting agencies.
This represents a 105% increase from 2024’s reported use cases, which came in at 1,757.
Pursuant to several executive actions and congressional laws, including the 2023 National Defense Authorization Act and an April 2025 memo from the Office of Management and Budget, federal agencies are required to report how AI tools are being used in their operations.
OMB is the only office agencies are required to report to, the agency confirmed, adding that use cases employed by the Intelligence Community and Pentagon are exempted from reporting, and other agencies are exempted from reporting National Security use cases. The complete repository was last updated on April 14.
The Department of Health and Human Services reported the most active use cases at 447 — a sizable leap from the 271 reported in 2024. Trailing HHS with the largest number of use cases are NASA, the Department of Veterans Affairs, the Department of Energy, and the Department of Justice, reporting 425, 367, 340 and 314, respectively.
HHS drove the growth in AI acquisition both in 2024 as well as in 2025.
Use case rationales are diverse. Text identification, summarization and manipulation; data analytics and pattern recognition; predictive modeling; and chatbot services were all listed as common use case areas in both high- and low-impact programs.
Of the 445 reported use cases that were deemed “high-impact,” Veterans Affairs reported using the most, with 215 high-impact cases. Some of these include: “Summarization of Clinical Data;” “Forescout: AI Behavioral Anomaly Detection w/ Automated Enforcement;” and “VA VoiceBot for Call Center Modernization.”
AI was also applied in some high-impact use cases to focus on natural language processing for text analysis, machine intelligence for small satellites, science translation and identity verification.
Agencies also listed the software providers they were contracting with to support each of the use cases in their respective inventories. Microsoft’s products dominated the list, with 102 use cases operating with a version of the company’s Copilot AI tool.
Anthropic’s Claude was also a frequently mentioned commercial-off-the-shelf solution used in government AI 25 times, with most use cases coming from the Department of State and HHS. Since the fallout between Anthropic and the Pentagon over the company refusing to allow its AI to be used in surveillance and autonomous weapons, the Trump administration subsequently ordered federal agencies to shed their contracts with the company and stop using its software.