For the Apollo engines, it's one if by space, two if by sea.
On July 16, 1969, a rocket in Cape Canaveral, Florida launched three humans into space, destination moon. They were hurtled away from Earth with the help of NASA's Saturn V rocket -- and with the help of, at the rocket's base, five Rocketdyne F-1 engines. This was a lot of help. According to a 1965 press release [pdf], "The F-1 is the most powerful rocket engine to be ordered into production in the United States. It is a single chamber, liquid propellant engine of conventional, proven design developing 1,500,000 pounds of thrust." And despite all the advances we've made since then in the broad field of rocket science, the F-1 remains the most powerful single-chamber liquid-fueled rocket engine ever developed.
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